Which test fits this patient?
Pick the clinical picture. The navigator ranks the available panels by how well they cover the genes or antibodies that matter for that picture, and shows what each one misses. No-cost sponsored panels are listed first when coverage is comparable.
Coverage grid
For a chosen clinical picture, which panel tests which key gene. Filled dot: on the panel. Ring: available only as a preliminary-evidence add-on. Empty: not tested.
Antibody pictures show Wash U syndrome panels instead of genes.
Panels
Every panel currently in the navigator, with cost, eligibility, ordering links, and the full gene or antibody list.
Gene lookup
Type a gene symbol to see which panels include it and what phenotype the NeuroNavigATTR guide assigns it.
For patients: what these tests are
Plain-language answers to the questions people bring to clinic after hearing "we'd like to do genetic testing" or "we're sending an antibody panel."
What is a genetic panel?
A single blood or saliva sample is read for changes in a set of genes known to cause inherited nerve or muscle disease. "Panel" just means many genes are checked at once. The panels on this site check between 66 and 211 genes.
What is an antibody panel?
Some nerve and muscle diseases are caused by the immune system attacking nerve or muscle. An antibody panel looks in blood for the specific antibodies that mark those conditions. Finding one can point to a treatable cause. These tests do not look at your genes.
What does "sponsored" or "no-cost" mean?
A drug company pays the laboratory so that neither you nor your insurance is billed for the test. Programs have eligibility rules (for example, age, symptoms, or a family history), and your doctor must confirm you meet them. Your results belong to you; the sponsor typically receives only de-identified data. Ask your doctor what the specific program shares.
Will a negative result mean my condition isn't inherited?
No. A panel only checks the genes on its list. Some causes of inherited neuropathy are not on the sponsored panels (for example, the gene MME is not on NeuroNavigATTR, and SORD needs a separate urine test because standard panels cannot read it reliably). A negative result may lead your doctor to suggest a broader panel.
Can the genetic test tell me if I have amyloidosis?
Only the hereditary form. The TTR gene test checks for hereditary transthyretin amyloidosis. It cannot detect AL amyloidosis, which is acquired and needs blood and urine protein tests and sometimes a tissue biopsy.
What is a "variant of uncertain significance"?
A change in a gene that the laboratory cannot yet classify as harmful or harmless. It is common, and it usually does not change your care on its own. Genetic counseling helps put it in context; the NeuroNavigATTR program includes free counseling.
How long do results take?
Two to three weeks for most genetic panels; antibody panels vary by test.
Sources and maintenance
Gene lists, antibody groupings, eligibility and turnaround times were taken from the laboratories' own pages on September 11, 2026:
- NeuroNavigATTR (PreventionGenetics, sponsored by AstraZeneca): program page and the 74-gene clinical guide PDF supplied by the program.
- Labcorp Genetics (Invitae) Comprehensive Neuropathies Panel (test 899863) and Comprehensive Neuromuscular Disorders Panel (test 899907): Labcorp test menu, updated 07/29/2026 for 899907.
- The Lantern Project (Revvity Omics, sponsored by Sanofi): Focused Neuromuscular Disease Panel and Pain and Cerebrovascular Panel pages.
- Labcorp Genetics (Invitae) ALS with C9orf72 Panel (900127) and C9orf72 Repeat Expansion Test (900169): Labcorp test menu.
- GeneDx and Athena Diagnostics DM1/DM2 repeat-expansion test summaries; Myotonic Dystrophy Foundation testing guidance; DM best-practice guidelines (Kamsteeg 2012, Eur J Hum Genet).
- Peter and Takako Jones Lab (University of Nevada, Reno School of Medicine) FSHD saliva methylation research test, via MyFSHD and FSHD Global Research Foundation program pages.
- University of Iowa Diagnostic Laboratories (UIDL) FSHD1/FSHD2 test pages and requisition; Statland 2021 (Neurology) CLIA laboratory retrospective analysis of UIDL FSHD testing; Athena Diagnostics FSHD1 Southern Blot Test; FSHD Society genetic testing guide; FSHD2/SMCHD1 literature (de Greef 2015, Eur J Hum Genet; Giardina 2024 best-practice update, Clinical Genetics).
- Mayo Clinic Laboratories sorbitol/xylitol assays (620920 urine, 623501 blood) and the SORD pseudogene literature (Lassuthova 2021, Sci Rep; Cortese 2020).
- Washington University Neuromuscular Clinical Laboratory: Antibody & Serum Tests request form, rev. 7/22/2025.
Sponsored programs can change scope or end without notice, and labs add and remove genes. Before ordering, confirm current gene content and eligibility on the requisition form. Two counts worth knowing: the NeuroNavigATTR clinical guide lists 73 distinct genes while the panel is marketed as 74; and the Lantern pain panel description mentions IDUA reflex testing though IDUA is not in its published gene list.
Phenotype "key gene" sets used by the ranking were assembled by the Hoag Neuromuscular Program from the NeuroNavigATTR guide and standard references; they drive the ranking and are editable in the page source under PHENOTYPES.
Understanding the conditions
Background on each disease this site tests for — what causes it, how the subtypes differ, and why testing is structured the way it is. Start with the condition below; more entries (CMT subtypes, LGMD subtypes, FSHD, hATTR) are being added.